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Can I read Molecular Changes Associated With Replication of Simian Immunodeficiency Virus in Human Cells on EtoBox?
Molecular Changes Associated With Replication of Simian Immunodeficiency Virus in Human Cells by Toshiaki Kodama; Dawn P.W. Burns; Harry W. Kestler; Muthiah D. Daniel; Ronald C. Desrosiers is a Immunology and Microbiology article available to read on EtoBox.
What is Molecular Changes Associated With Replication of Simian Immunodeficiency Virus in Human Cells about?
The SIVmac239 infectious clone does not have a premature stop codon in its transmembrane protein (TMP) region and it produces full‐length (41 kilodalton, kDa) TMP in macaque peripheral blood lymphocytes (PBL) in vitro and in vivo. However, viruses with truncated forms of TMP (28kDa) are selected during propagation in human cell types; truncated forms arise from point mutations. CAG (glutamine) to TAG (stop), in the viral genome. These results document molecular changes associated with adaptation of SIV‐mac for growth in human cells.
Who reads Molecular Changes Associated With Replication of Simian Immunodeficiency Virus in Human Cells?
It is typically read by researchers, students, and practitioners in Immunology and Microbiology.
- Author
- Toshiaki Kodama; Dawn P.W. Burns; Harry W. Kestler; Muthiah D. Daniel; Ronald C. Desrosiers
- Publisher
- Wiley
- Published
- 1990
- Language
- EN
- Field
- Immunology and Microbiology (Life Sciences)