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Characterization of an NDM-5 carbapenemase-producing Escherichia coli ST156 isolate from a poultry farm in Zhejiang, China by Tang, Biao; Chang, Jiang; Cao, Liujie; Luo, Qixia; Xu, Hao; Lyu, Wentao; Qian, Mingrong; Ji, Xiaofeng; Zhang, Qiaoyan; Xia, Xiaodong; Yang, Hua is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.
What is Characterization of an NDM-5 carbapenemase-producing Escherichia coli ST156 isolate from a poultry farm in Zhejiang, China about?
## Background: The emergence of carbapenem-resistant enterobacteriaceae strains has posed a severe threat to public health in recent years. the mobile elements carrying the new delhi metallo-β-lactqtamase (ndm) gene have been regarded as the major mechanism leading to the rapid increase of carbapenem-resistant enterobacteriaceae strains isolated from clinics and animals. ## Results: We describe an ndm-5-producing escherichia coli strain, eccra-119 (sequence type 156 [st156]), isolated from a poultry farm in zhejiang, china. eccra-119 is a multidrug-resistant (mdr) isolate that exhibited resistance to 27 antimicrobial compounds, including imipenem and meropenem, as detected by antimicrobial susceptibility testing (ast). the complete genome sequence of the eccra-119 isolate was also obtained using the pacbio rs ii platform. eleven acquired resistance genes were identified in the chromosome; four were detected in plasmid ptb201, while six were detected in plasmid ptb202. importantly, the carbapenem-resistant gene bla was detected in the incx3 plasmid ptb203. in addition, seven virulence genes and one metal-resistance gene were also detected. the results of conjugation experiments and
Who reads Characterization of an NDM-5 carbapenemase-producing Escherichia coli ST156 isolate from a poultry farm in Zhejiang, China?
It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.
- Author
- Tang, Biao; Chang, Jiang; Cao, Liujie; Luo, Qixia; Xu, Hao; Lyu, Wentao; Qian, Mingrong; Ji, Xiaofeng; Zhang, Qiaoyan; Xia, Xiaodong; Yang, Hua
- Publisher
- BioMed Central; Springer (Biomed Central Ltd.); London: BioMed Central, 2001-; Springer Science and Business Media LLC; Society for Mining, Metallurgy and Exploration Inc. (ISSN 1471-2180)
- Published
- 2019
- Language
- EN
- Field
- Biochemistry, Genetics and Molecular Biology (Life Sciences)