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Continuous Epidural Butorphanol Relieves Pruritus Associated with Epidural Morphine Infusions in Children by J.B. Gunter; J. Mcauliffe; T. Gregg; N. Weidner; A.M. Varughese; D.M. Sweeney is a Medicine article available to read on EtoBox.

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## Summary We examined the efficacy of epidural butorphanol to either prevent or relieve pruritus associated with epidural morphine infusion in children. Forty‐six children were randomized to receive either epidural morphine (M) or epidural M with butorphanol (B) for postoperative analgesia. They received bupivacaine and either M 50 μg·kg^−1^ or the same dose of M plus B 10 μg·kg^−1^. Following surgery, a continuous infusion of 0.1% bupivacaine with either M 20 μg·ml^−1^ or M 20 μg·ml^−1^+ B 4 μg·ml^−1^ was given at a rate of 0.3 ml·kg^−1^·h^−1^. Pain scores and pruritus scores were recorded every 4 h during epidural infusion. Subjects with a pruritus score=2 received diphenhydramine 0.5 mg·kg^−1^ i.v. and were switched to an alternate epidural infusion; subjects receiving M (group M) were switched to M+B while subjects receiving M+B (group B) were switched to hydromorphone (H) 4 μg·ml^−1^. There was no difference in the initial incidence of pruritus (group M 11/18; group B 13/28). No subject in group M required a second change of epidural infusion because of continued pruritus after being switched to M+B; five of 13 subjects in group B continued to experience pruritus after being

Who reads Continuous Epidural Butorphanol Relieves Pruritus Associated with Epidural Morphine Infusions in Children?

Author

J.B. Gunter; J. Mcauliffe; T. Gregg; N. Weidner; A.M. Varughese; D.M. Sweeney

Publisher

John Wiley and Sons; Wiley (Blackwell Publishing); Blackwell Publishing Inc.; Wiley (ISSN 1155-5645)

Published

2000

Language

EN

Field

Medicine (Health Sciences)