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This systematic review and network meta-analysis evaluated the efficacy of prophylactic anticonvulsant drugs in preventing post-traumatic seizures (PTS) following traumatic brain injury, analyzing 11 randomized controlled trials with 2,450 participants. The findings indicated that while anticonvulsant drugs significantly reduced early PTS compared to placebo, no specific drug was superior in preventing either early or late PTS, although phenytoin showed potential in preventing early PTS in a sensitivity ana

Author

BoCyuan Wang

Language

EN