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This document summarizes the formulation and evaluation of medicated chewing gum containing ondansetron HCl for treating chemotherapy-induced nausea and vomiting. Several batches of chewing gum were prepared using different concentrations of polymers, plasticizers, and other excipients. The batches were evaluated for weight variation, friability, texture analysis, and in vitro drug release. The best formulation was batch FR4, which had gumminess of 8126.33, chewiness of 6144.29, and resilience of 0.725. Thi

Author

Muhammad Jamil

Language

EN