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Comparison of atrial fibrillation in CKD and non-CKD populations: A cross-sectional analysis from the Kailuan study by Yidan Guo; Jingli Gao; Pengpeng Ye; Aijun Xing; Yuntao Wu; Shouling Wu; Yang Luo is a Medicine article available to read on EtoBox.

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## Objectives: To compare clinical epidemiological features of atrial fibrillation (af) in chronic kidney disease (ckd) and non-ckd populations. ## Methods: This study included 88,312 adults aged ≥45 years old from the kailuan study. af was ascertained with a 12-lead electrocardiogram. ckd was defined as an estimated glomerular filtration rate (egfr) 60 ml/min/1.73 m without proteinuria, n = 66,725) and ckd (n = 21,578) groups. we evaluated the prevalence of af in both groups, evaluated risk factors for af using multivariable-adjusted logistic regression analysis. ## Results: The prevalence of af among non-ckd and ckd participants was 0.26% and 1.00%, respectively. multivariable-adjusted analysis showed that older age (odds ratio [or]: 1.08, 95% confidence interval [ci]: 1.07-1.10, p < 0.001), smoking (or: 1.23, 95% ci: 1.07-1.57, p = 0.017), hypertension (or: 2.14, 95% ci: 1.44-3.17, p < 0.001), diabetes (or: 1.79, 95% ci: 1.10-2.89, p < 0.001), and larger waist circumference (or: 1.03, 95% ci: 1.01-1.04, p < 0.001) were significantly associated with af in the non-ckd group. in the ckd group, older age, smoking, larger waist circumference, reduced egfr (or: 0.97, 95% ci: 0.95-0.

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Author

Yidan Guo; Jingli Gao; Pengpeng Ye; Aijun Xing; Yuntao Wu; Shouling Wu; Yang Luo

Publisher

Elsevier BV

Published

2018

Language

EN

Field

Medicine (Health Sciences)