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Can I read Monoclonal Human Auto-antibodies: Novel Tools for the Understanding and Treatment of Neuropsychiatric Symptoms on EtoBox?
Monoclonal Human Auto-antibodies: Novel Tools for the Understanding and Treatment of Neuropsychiatric Symptoms by Harald Prüss is a Psychology article available to read on EtoBox.
What is Monoclonal Human Auto-antibodies: Novel Tools for the Understanding and Treatment of Neuropsychiatric Symptoms about?
The various clinical manifestations of autoimmune encephalitis made this disease group an exciting new field in Neurology and Psychiatry. Identification of numerous pathogenic auto-antibodies against neuronal tissue resulted in unprecedented diagnostic and therapeutic opportunities. This has led to a critical reappraisal also of symptoms in patients with psychosis and dementia, and in some instances resulted in re-classification of disease. We now increasingly generate patient-derived monoclonal auto-antibodies against neuronal surface proteins and demonstrate their direct pathogenicity to cause neuropsychiatric symptoms. This has two essential implications: First, patients with these types of pathogenic auto-antibodies harbour a clear risk factor for the development of psychiatric abnormalities. Second, given their pathogenicity, the primary goal of treatment must be the removal of auto-antibodies using state-of-the-art immunotherapy rather than symptomatic treatment including neuroleptics. The technological achievement of recombinant generation of disease-causing human auto-antibodies will allow in the future i) to clarify the specific role of a given auto-antibody for the diseas
Who reads Monoclonal Human Auto-antibodies: Novel Tools for the Understanding and Treatment of Neuropsychiatric Symptoms?
It is typically read by researchers, students, and practitioners in Psychology.
- Author
- Harald Prüss
- Publisher
- Elsevier BV
- Published
- 2023
- Language
- EN
- Field
- Psychology (Social Sciences)