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Can I read Electron Tunneling Through Sensitizer Wires Bound to Proteins on EtoBox?
Electron Tunneling Through Sensitizer Wires Bound to Proteins by Matthew R. Hartings; Igor V. Kurnikov; Alexander R. Dunn; Jay R. Winkler; Harry B. Gray; Mark A. Ratner is a Chemistry article available to read on EtoBox.
What is Electron Tunneling Through Sensitizer Wires Bound to Proteins about?
We report a quantitative theoretical analysis of long-range electron transfer through sensitizer wires bound in the active-site channel of cytochrome P450cam. Each sensitizer wire consists of a substrate group with high binding affinity for the enzyme active site connected to a ruthenium-diimine through a bridging aliphatic or aromatic chain. Experiments have revealed a dramatic dependence of electron transfer rates on the chemical composition of both the bridging group and the substrate. Using combined molecular dynamics simulations and electronic coupling calculations, we show that electron tunneling through perfluorinated aromatic bridges is promoted by enhanced superexchange coupling through virtual reduced states. In contrast, electron flow through aliphatic bridges occurs by hole-mediated superexchange. We have found that a small number of wire conformations with strong donor-acceptor couplings can account for the observed electron tunneling rates for sensitizer wires terminated with either ethylbenzene or adamantane. In these instances, the rate is dependent not only on electronic coupling of the donor and acceptor but also on the nuclear motion of the sensitizer wire, neces
Who reads Electron Tunneling Through Sensitizer Wires Bound to Proteins?
It is typically read by researchers, students, and practitioners in Chemistry.
- Author
- Matthew R. Hartings; Igor V. Kurnikov; Alexander R. Dunn; Jay R. Winkler; Harry B. Gray; Mark A. Ratner
- Publisher
- Elsevier Science; Elsevier ; Elsevier BV (ISSN 0010-8545)
- Published
- 2010
- Language
- EN
- Field
- Chemistry (Physical Sciences)