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Regulation of H.M.G.-CoA reductase by Benjamin Preiss (Eds.) is a nonfiction available to read on EtoBox.

What is Regulation of H.M.G.-CoA reductase about?

Regulation of HMG-CoA Reductase is a nine-chapter text that focuses on the research developments in the regulation of HMG-CoA reductase enzyme and cholesterol biosynthesis. This book deals first with the role of cholesterol in the regulation of its own biosynthesis and the work involving compactin and related competitive inhibitors of HMG-CoA reductase. The subsequent chapters examine the reversible phosphorylation of HMG-CoA reductase in hormonal and other short-term physiological changes and the structure and properties of the enzyme, including evidence for modulation of enzyme activity and structure unrelated to phosphorylation. These topics are followed by discussions on the regulation of reductase in the biosynthesis of ubiquinone, dolichols, and isopentenyl-tRNA and the regulation of reductase activity in extrahepatic tissues. This text further explores the contributions made through the use of cultured cells and their genetic manipulation, with emphasis on the great potential of this approach. The concluding chapters address the status of the low-density lipoprotein pathway and related mechanisms. These chapters also consider the regulation of human hepatic HMG-CoA reductase

Who reads Regulation of H.M.G.-CoA reductase?

Author

Benjamin Preiss (Eds.)

Publisher

Academic Press, Incorporated

Published

1985

Language

EN

ISBN

9780125644303

Category

nonfiction

Subjects

Nature, Science, Chemistry