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Determinants of Quality of Life in Acute Heart Failure Patients with and Without Comorbidities: a Prospective, Observational Study by Jan C van den Berge; Laura C van Vark; Douwe Postmus; Elisabeth M W J Utens; Hans L Hillege; Eric Boersma; Ivonne Lesman-Leegte; K Martijn Akkerhuis is a Medicine article available to read on EtoBox.

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## Abstract ## Aims The relation between non-cardiac comorbidities and health-related quality of life (HRQoL) in patients with heart failure (HF) has been studied to a limited extent. To investigate the HRQoL and their determinants among HF patients with and without comorbidities. ## Methods and results TRIUMPH (TRanslational Initiative on Unique and novel strategies for Management of Patients with Heart failure) is a Dutch prospective, multicentre study enrolling 496 acute HF patients between 2009 and 2014. We included 334 patients who had completed the HRQoL questionnaires at baseline. The HRQoL was measured by the Kansas City Cardiomyopathy Questionnaire (KCCQ) en EuroQuality-of-life five Dimensions (EQ-5D). Comorbidity was defined as having a history of at least one of the following comorbidities: chronic kidney disease, diabetes mellitus, chronic obstructive pulmonary disease (COPD), and/or cerebrovascular accident. Patients with comorbidity (n = 205, 61%) had lower scores on the physical limitation scale and clinical summary score of the KCCQ (P = 0.03 and P = 0.01, respectively). Female sex, COPD, previous HF, increasing body mass index (BMI), elevated N-terminal pro-B-type

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Author

Jan C van den Berge; Laura C van Vark; Douwe Postmus; Elisabeth M W J Utens; Hans L Hillege; Eric Boersma; Ivonne Lesman-Leegte; K Martijn Akkerhuis

Publisher

Oxford University Press (OUP)

Published

2021

Language

EN

Field

Medicine (Health Sciences)