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The development of non‐resorbable bone allografts: Biological background and clinical perspectives by Richard J. Miron; Masako Fujioka‐Kobayashi; Michael A. Pikos; Toshiaki Nakamura; Takatomo Imafuji; Yufeng Zhang; Yukiya Shinohara; Anton Sculean; Yoshinori Shirakata is a Dentistry article available to read on EtoBox.

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## Abstract Bone grafts are typically categorized into four categories: autografts, allografts, xenografts, and synthetic alloplasts. While it was originally thought that all bone grafts should be slowly resorbed and replaced with native bone over time, accumulating evidence has in fact suggested that the use of nonresorbable xenografts is favored for certain clinical indications. Thus, many clinicians take advantage of the nonresorbable properties/features of xenografts for various clinical indications, such as contour augmentation, sinus grafting, and guided bone regeneration, which are often combined with allografts (e.g., human freeze‐dried bone allografts [FDBAs] and human demineralized freeze‐dried bone allografts [DFDBAs]). Thus, many clinicians have advocated different 50/50 or 70/30 ratios of allograft/xenograft combination approaches for various grafting procedures. Interestingly, many clinicians believe that one of the main reasons for the nonresorbability or low substitution rates of xenografts has to do with their foreign animal origin. Recent research has indicated that the sintering technique and heating conducted during their processing changes the dissolution rate

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Author

Richard J. Miron; Masako Fujioka‐Kobayashi; Michael A. Pikos; Toshiaki Nakamura; Takatomo Imafuji; Yufeng Zhang; Yukiya Shinohara; Anton Sculean; Yoshinori Shirakata

Publisher

Wiley

Published

2024

Language

EN

Field

Dentistry (Health Sciences)