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Can I read PCOS in Adolescents—Ongoing Riddles in Diagnosis and Treatment on EtoBox?
PCOS in Adolescents—Ongoing Riddles in Diagnosis and Treatment by Blazej Meczekalski; Olga Niwczyk; Anna Kostrzak; Marzena Maciejewska-Jeske; Gregory Bala; Anna Szeliga is a Medicine article available to read on EtoBox.
What is PCOS in Adolescents—Ongoing Riddles in Diagnosis and Treatment about?
Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders in women of reproductive age. A diagnosis of PCOS is established when a patient exhibits two of three Rotterdam criteria: oligoovulation or anovulation, excess androgen activity, and polycystic ovarian morphology. The pathogenesis of PCOS, as it affects adolescents, is often discussed in terms of a “two-hit” theory. This refers to a stepwise process in which the first “hit” is an inborn congenitally programmed predisposition, while the second “hit” arises from a provocative factor such as insulin resistance. The dynamic physiological and anatomical changes which occur in puberty make for a challenging diagnosis in this group of patients. It is important to be mindful of the physiological particularities in adolescence which often mimic the symptoms of PCOS. In their first-year post-menarche, approximately 75% of menstruating adolescents report their cycle to last between 21–45 days. Recent studies have shown that regular menstrual cyclicity is only achieved within 2–3 years post-menarche. Anovulation, as a crucial diagnostic element for PCOS, features in about half of early-post-menarchal adolescents. Hi
Who reads PCOS in Adolescents—Ongoing Riddles in Diagnosis and Treatment?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Blazej Meczekalski; Olga Niwczyk; Anna Kostrzak; Marzena Maciejewska-Jeske; Gregory Bala; Anna Szeliga
- Publisher
- MDPI AG
- Published
- 2023
- Language
- EN
- Field
- Medicine (Health Sciences)