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Development of Tolerance To The Analgesic Activity of Mu Agonists After Continuous LN Fusion of Morphine, Meperidine or Fentanyl in Rats by yunus is a document available to read on EtoBox.
This study investigates the development of tolerance to the analgesic effects of mu agonists following continuous infusion of morphine, meperidine, or fentanyl in rats. Results indicate that the extent of tolerance varies with the intrinsic activity of the mu agonists used, with morphine and meperidine producing more tolerance than fentanyl. The findings suggest that the potency and efficacy of different mu agonists play a significant role in the development of analgesic tolerance.
- Author
- yunus
- Language
- EN