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Evidence for structurally specific negative feedback in the Nod factor signal transduction pathway by Giles E. D. Oldroyd; Raka M. Mitra; Rebecca J. Wais; Sharon R. Long is a Agricultural and Biological Sciences article available to read on EtoBox.
What is Evidence for structurally specific negative feedback in the Nod factor signal transduction pathway about?
## Summary Nod factor is a critical signalling molecule in the establishment of the legume/rhizobial symbiosis. The Nod factor of __Sinorhizobium meliloti__ carries __O__‐sulphate, __O__‐acetate and C~16:2~__N__‐acyl attachments that define its activity and host specificity. Here we assess the relative importance of these modifications for the induction of calcium spiking in __Medicago truncatula__. We find that Nod factor structures lacking the __O__‐sulphate, structures lacking the __O__‐acetate and __N__‐acyl groups, and structures lacking the __O__‐acetate combined with a C~18:1~__N__‐acyl group all show calcium spiking when applied at high concentrations. These calcium responses are blocked in __dmi1__ and __dmi2__ mutants, suggesting that they function through the Nod factor signal transduction pathway. The __dmi3__ mutant, which is proposed to function in the Nod factor signal transduction pathway downstream of calcium spiking, shows increased sensitivity to Nod factor. This increased sensitivity is only active with wild‐type Nod factor and was not present when the plants were treated with mutant Nod factor structures. We propose that the Nod factor signal transduction pathw
Who reads Evidence for structurally specific negative feedback in the Nod factor signal transduction pathway?
It is typically read by researchers, students, and practitioners in Agricultural and Biological Sciences.
- Author
- Giles E. D. Oldroyd; Raka M. Mitra; Rebecca J. Wais; Sharon R. Long
- Publisher
- John Wiley and Sons; Wiley (Blackwell Publishing); Blackwell Publishing Inc.; Wiley (ISSN 0960-7412)
- Published
- 2001
- Language
- EN
- Field
- Agricultural and Biological Sciences (Life Sciences)