About this scholarly article

Non‐invasive hemodynamic profile of early COVID‐19 infection by Busana, Mattia; Schiavone, Marco; Lanfranchi, Antonio; Battista Forleo, Giovanni; Ceriani, Elisa; Beatrice Cogliati, Chiara; Gasperetti, Alessio is a scholarly article available to read on EtoBox.

## Introduction: Little is known about the systemic and pulmonary macrohemodynamics in early covid-19 infection. echocardiography may provide useful insights into covid-19 physiopathology. ## Methods: Twenty-three covid-19 patients were enrolled in a medical ward. gas exchange, transthoracic echocardiographic, and hemodynamic variables were collected. ## Results: Mean age was 57 ± 17 years. the patients were hypoxemic (pao /fio = 273.0 ± 102.6 mmhg) and mildly hypocapnic (paco = 36.2 ± 6.3 mmhg, ph = 7.45 ± 0.03). mean arterial pressure was decreased (86.7 [80.0-88.3] mmhg). cardiac index was elevated (4.32 ± 0.90 l∙min ∙m ) and the resulting systemic vascular resistance index low (1,458 [1358-1664] dyn∙s∙cm ∙m ). the right heart was morphologically and functionally normal, with pulmonary artery pressure (papm, 18.0 ± 2.9 mmhg) and total pulmonary resistances (tpr, 2.3 [2.1-2.7] mmhg∙l ∙min ) within normal limits. when stratifying for svri, patients with an svri value below the cohort median had also more severe oxygenation impairment and lower tpr, despite a similar degree of cxr infiltrates. oxygen delivery index in this group resulted supranormal. ## Conclusions: In the early

Author

Busana, Mattia; Schiavone, Marco; Lanfranchi, Antonio; Battista Forleo, Giovanni; Ceriani, Elisa; Beatrice Cogliati, Chiara; Gasperetti, Alessio

Publisher

Wiley (Physiological Reports); John Wiley and Sons Inc.; Wiley; Research Square (ISSN 2051-817X)

Published

2020

Language

EN