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What is Characterization of α-casozepine Peptide about?

This document describes research characterizing a peptide called α-casozepine derived from bovine αs1-casein. α-Casozepine was found to have benzodiazepine-like anxiolytic and anticonvulsant effects in rat models when administered orally. It binds to the GABAA receptor, though with much lower affinity than diazepam. Surprisingly, α-casozepine was found to be 10 times more effective than diazepam in one rat anxiety model despite its lower receptor affinity. The peptide does not bind to the peripheral-type be

Author

AnAn BanhGao

Language

EN