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What is CTNNB1 Mutations and Imatinib Efficacy about?

This study investigates the correlation between CTNNB1 mutation status and progression arrest rate in patients with desmoid-type fibromatosis (DF) treated with imatinib. Results show that patients with the S45F mutation had a significantly higher progression arrest rate (85%) compared to wild-type patients (43%), suggesting the mutation may serve as a predictive marker for treatment response. The findings support the potential utility of CTNNB1 mutation analysis in guiding treatment decisions for DF patient

Author

laraib

Language

EN