Can I read Pentraxin 3 in Amniotic Fluid: a Novel Association with Intra-amniotic Infection and Inflammation on EtoBox?
Pentraxin 3 in Amniotic Fluid: a Novel Association with Intra-amniotic Infection and Inflammation by Laura Cruciani; Roberto Romero; Edi Vaisbuch; Juan Pedro Kusanovic; Tinnakorn Chaiworapongsa; Shali Mazaki-Tovi; Pooja Mittal; Giovanna Ogge; Francesca Gotsch; Offer Erez; Sun Kwon Kim; Zhong Dong; Percy Pacora; Ronald F. Lamont; Lami Yeo; Sonia S. Hassan; Gian Carlo Di Renzo is a Medicine article available to read on EtoBox.
What is Pentraxin 3 in Amniotic Fluid: a Novel Association with Intra-amniotic Infection and Inflammation about?
Objective: Pentraxin 3 (PTX3) is a soluble pattern recognition receptor (PRR) that has an important role in immunoregulation and vascular integrity. The aim of this study was to determine if PTX3 is present in amniotic fluid (AF) and whether its concentration changes with gestational age (GA), in the presence of preterm or term labor, and in cases of intra-amniotic infection/inflammation (IAI) associated with spontaneous preterm labor (PTL) or preterm prelabor rupture of membranes (PROM). Study design: This cross-sectional study included the following groups: 1) mid-trimester (ns45); 2) uncomplicated pregnancies at term with (ns48) and without (ns40) spontaneous labor; 3) women with PTL and intact membranes who: a) delivered at term (ns44); b) delivered preterm without IAI (ns40); or c) delivered preterm with IAI (ns62); 4) women with preterm PROM with (ns63) and without (ns36) IAI. PTX3 concentration in AF was determined by ELISA. Non-parametric statistics were used for analyses. Results: 1) Among women with PTL and intact membranes, the median AF PTX3 concentration was significantly higher in women with IAI than in those without IAI (7.95 ng/mL
Who reads Pentraxin 3 in Amniotic Fluid: a Novel Association with Intra-amniotic Infection and Inflammation?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Laura Cruciani; Roberto Romero; Edi Vaisbuch; Juan Pedro Kusanovic; Tinnakorn Chaiworapongsa; Shali Mazaki-Tovi; Pooja Mittal; Giovanna Ogge; Francesca Gotsch; Offer Erez; Sun Kwon Kim; Zhong Dong; Percy Pacora; Ronald F. Lamont; Lami Yeo; Sonia S. Hassan; Gian Carlo Di Renzo
- Publisher
- Walter de Gruyter GmbH
- Published
- 2010
- Language
- EN
- Field
- Medicine (Health Sciences)