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Exhaled Nitric Oxide Corresponds with Office Evaluation of Asthma Control by Isabelle Meyts; Marijke Proesmans; Kris De Boeck is a Medicine article available to read on EtoBox.

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## Abstract Exhaled NO (ENO) has been studied as a noninvasive marker of airway inflammation, and has been shown to be elevated in asthma patients. The aim of this study was to investigate whether ENO measurements differ significantly between groups of asthmatic children with different disease control and to compare ENO measurements with the clinical assessment of asthma control. Seventy‐three children between 5–18 years old with a diagnosis of asthma were recruited. ENO was measured online during a slow vital capacity maneuver. The mean of three plateau NO levels was used for analysis. Baseline and postbronchodilator spirometry were performed. The assessment of disease control was based on the frequency of use of beta2‐agonists, occurrence of day‐ and nighttime asthma symptoms, and spirometry results. Twenty‐one children (group 1) had good asthma control. In 31 patients (group 2), asthma control was acceptable. In 21 patients (group 3), asthma was insufficiently controlled. ENO levels were (median (quartiles)): group 1, 11 ppb (9–21); group 2, 15 ppb (11–26); and group 3, 28 ppb (19–33). Measurements were significantly different between all three groups (__P__ = 0.009, Kruskal‐Wal

Who reads Exhaled Nitric Oxide Corresponds with Office Evaluation of Asthma Control?

Author

Isabelle Meyts; Marijke Proesmans; Kris De Boeck

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 8755-6863)

Published

2003

Language

EN

Field

Medicine (Health Sciences)