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Drug metabolism : current concepts : edited by Corina Ionescu, Mino R. Caira by Caira, Mino R.;Ionescu, Corina is a nonfiction available to read on EtoBox.

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Provides a comprehensive understanding of the processes that take place following ingestion of a medicinal agent or xenobiotic, with an emphasis on the crucial role of metabolism (biotransformation). This book also explains how a sound knowledge of these phenomena is incorporated into the design of effective new drug candidates.;Machine derived contents note: CHAPTER 1. DRUG METABOLISM IN CONTEXT 1 -- 1.1 INTRODUCTION -- 1.2 ABSO RPTION 3 -- 1.2.1 Basic mechanisms of transport through membranes 17 -- 1.3 DRUG DISTRIBUTION 21 -- 1.3.1 Qualitative aspects 21 -- 1.3.2 Kinetic aspects 22 -- 1.4 DYNAMICS OF DRUG ACTION 25 -- 1.4.1 Drug-receptor interaction 25 -- 1.4.2 Mechanisms 27 -- 1.4.3 Further aspects 28 -- 1.5 DRUG CLEARANCE 29 -- 1.5.1 Drug metabolism 29 -- 1.5.2 Excretion 32 -- 1.6 DYNAMICS OF DRUG CLEARANCE 33 -- 1.6.1 Basic pharmacokinetic parameters 34 -- References 37 -- CHAPTER 2. PATHWAYS OF BIOTRANSFORMATION -- PHASE I -- REACTIONS 41 -- 2.1 INTRODUCTION 41 -- 2.2 PHASE I AND PHASE II METABOLISM: GENERAL -- CONSIDERATIONS 42 -- 2.3 OXIDATIONS INVOLVING THE MICROSOMAL -- MIXED-FUNCTION OXIDASE SYSTEM 48 -- 2.3.1 Components of the enzyme system and selected miscellaneous ox

Who reads Drug metabolism : current concepts : edited by Corina Ionescu, Mino R. Caira?

Author

Caira, Mino R.;Ionescu, Corina

Publisher

Springer London, Limited

Published

2005

Language

EN

ISBN

9781402041419

Category

nonfiction

Subjects

Medical, Science, Chemistry