Can I read Comparative Genome Analysis of Three Euplotid Protists Provides Insights Into the Evolution of Nanochromosomes in Unicellular Eukaryotic Organisms on EtoBox?

Comparative Genome Analysis of Three Euplotid Protists Provides Insights Into the Evolution of Nanochromosomes in Unicellular Eukaryotic Organisms by Didi Jin; Chao Li; Xiao Chen; Adam Byerly; Naomi A. Stover; Tengteng Zhang; Chen Shao; Yurui Wang is a Environmental Science article available to read on EtoBox.

What is Comparative Genome Analysis of Three Euplotid Protists Provides Insights Into the Evolution of Nanochromosomes in Unicellular Eukaryotic Organisms about?

One of the most diverse clades of ciliated protozoa, the class Spirotrichea, displays a series of unique characters in terms of eukaryotic macronuclear (MAC) genome, including high fragmentation that produces nanochromosomes. However, the genomic diversity and evolution of nanochromosomes and gene families for spirotrich MAC genomes are poorly understood. In this study, we assemble the MAC genome of a representative euplotid (a new model organism in Spirotrichea) species, __Euplotes aediculatus__. Our results indicate that: (a) the MAC genome includes 35,465 contigs with a total length of 97.3 Mb and a contig N50 of 3.4 kb, and contains 13,145 complete nanochromosomes and 43,194 predicted genes, with the majority of these nanochromosomes containing tiny introns and harboring only one gene; (b) genomic comparisons between __E. aediculatus__ and other reported spirotrichs indicate that average GC content and genome fragmentation levels exhibit interspecific variation, and chromosome breaking sites (CBSs) might be lost during evolution, resulting in the increase of multi-gene nanochromosome; (c) gene families associated with chitin metabolism and FoxO signaling pathway are expanded in

Who reads Comparative Genome Analysis of Three Euplotid Protists Provides Insights Into the Evolution of Nanochromosomes in Unicellular Eukaryotic Organisms?

Author

Didi Jin; Chao Li; Xiao Chen; Adam Byerly; Naomi A. Stover; Tengteng Zhang; Chen Shao; Yurui Wang

Publisher

Springer Science and Business Media LLC

Published

2023

Language

EN

Field

Environmental Science (Physical Sciences)