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Berberis Vulgaris Root Bark Extract Prevents Hyperoxaluria Induced Urolithiasis in Rats by Samra Bashir; Anwar H. Gilani; Anwar A. Siddiqui; Shahid Pervez; Saeed R. Khan; Noor Jehan Sarfaraz; Abdul Jabbar Shah is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.
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## Abstract __Berberis vulgaris__ is a widely used plant for the treatment of urolithiasis. To evaluate its antiurolithic potential, the crude aqueous‐methanol extract of __Berberis vulgaris__ root bark (Bv.Cr) was tested in an animal model of urolithiasis, developed in male Wistar rats by adding 0.75% ethylene glycol in drinking water. Bv.Cr (50 mg/kg) inhibited CaOx crystal deposition in renal tubules and protected against associated changes including polyuria, weight loss, impaired renal function and the development of oxidative stress in kidneys. Activity‐guided fractionation revealed the concentration of antiurolithic constituent(s) mainly in the aqueous fraction. These data, indicating the presence of antiurolithic activity in __Berberis vulgaris__ root bark, rationalize its medicinal use for the treatment of urolithiasis. Copyright © 2010 John Wiley & Sons, Ltd.
Who reads Berberis Vulgaris Root Bark Extract Prevents Hyperoxaluria Induced Urolithiasis in Rats?
It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.
- Author
- Samra Bashir; Anwar H. Gilani; Anwar A. Siddiqui; Shahid Pervez; Saeed R. Khan; Noor Jehan Sarfaraz; Abdul Jabbar Shah
- Publisher
- John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0951-418X)
- Published
- 2010
- Language
- EN
- Field
- Biochemistry, Genetics and Molecular Biology (Life Sciences)