Opening book details…
Can I read Effects of non-invasive, 1,210 nm laser exposure on adipose tissue: Results of a human pilot study on EtoBox?
Effects of non-invasive, 1,210 nm laser exposure on adipose tissue: Results of a human pilot study by Molly Wanner; Mathew Avram; Denise Gagnon; Martin C. Mihm Jr.; David Zurakowski; Kanna Watanabe; Zeina Tannous; R. Rox Anderson; Dieter Manstein is a Medicine article available to read on EtoBox.
What is Effects of non-invasive, 1,210 nm laser exposure on adipose tissue: Results of a human pilot study about?
## Abstract ## Background and Objectives Laser radiation (1,210 nm) has been previously shown to be capable of selective photothermolysis of adipose tissue in vitro when applied non‐invasively. The objective of this pilot study was to evaluate the in vivo effects of this laser in human subjects. ## Study Design/Materials and Methods Twenty‐four adult subjects were exposed non‐invasively on the abdomen to a 1,210 nm laser at fluences of 70, 80, and 90 J/cm^2^, with a 10 mm spot size, 5 seconds pre‐cooling, and 3 seconds exposure duration delivered with parallel contact cooling. There was an impairment of the skin‐cooling device during the study. Exposure and control sites were biopsied at either 1–3 days or 4–7 weeks. Tissue was processed for nitroblue tetrazolium chloride (NBTC) staining, a marker for thermal damage, and hematoxylin and eosin (H&E) staining. ## Results Laser exposures were painful, requiring local anesthesia in most subjects, but otherwise well tolerated. At 1–3 days after exposure, there was a fluence‐dependent loss of NBTC staining in the fat and dermis. In 2 of 14 subjects (2 of 42 exposure sites) evaluated at 1–3 days after exposure, epidermal damage was noted
Who reads Effects of non-invasive, 1,210 nm laser exposure on adipose tissue: Results of a human pilot study?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Molly Wanner; Mathew Avram; Denise Gagnon; Martin C. Mihm Jr.; David Zurakowski; Kanna Watanabe; Zeina Tannous; R. Rox Anderson; Dieter Manstein
- Publisher
- John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0196-8092)
- Published
- 2009
- Language
- EN
- Field
- Medicine (Health Sciences)