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Can I read Selectively guanidinylated derivatives of neamine. Syntheses and inhibition of anthrax lethal factor protease on EtoBox?
Selectively guanidinylated derivatives of neamine. Syntheses and inhibition of anthrax lethal factor protease by Guan-Sheng Jiao; Ondrej Simo; Melissa Nagata; Sean O’Malley; Thomas Hemscheidt; Lynne Cregar; Sherri Z. Millis; Mark E. Goldman; Cho Tang is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.
What is Selectively guanidinylated derivatives of neamine. Syntheses and inhibition of anthrax lethal factor protease about?
A series of mono-, di-, and tri-guanidinylated derivatives of neamine were prepared via selective guanidinylation of neamine. These molecules represent a novel scaffold as inhibitors of anthrax lethal factor zinc metalloprotease. Methods for the synthesis of these compounds are described, and structure-activity relationships among the series are analyzed. In addition, initial findings regarding the mechanism of LF inhibition for these molecules are presented.
Who reads Selectively guanidinylated derivatives of neamine. Syntheses and inhibition of anthrax lethal factor protease?
It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.
- Author
- Guan-Sheng Jiao; Ondrej Simo; Melissa Nagata; Sean O’Malley; Thomas Hemscheidt; Lynne Cregar; Sherri Z. Millis; Mark E. Goldman; Cho Tang
- Publisher
- Elsevier Science; Elsevier ; Elsevier Ltd.; Elsevier BV (ISSN 0960-894X)
- Published
- 2006
- Language
- EN
- Field
- Biochemistry, Genetics and Molecular Biology (Life Sciences)