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Study the past if you would define the future (Confucius) by Keenan, Tiarnan D. (author);Chew, Emily Y. (author) is a Medicine article available to read on EtoBox.

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Li et al 1 reported the results of an elegant study to estimate the prevalence and incidence of age-related macular degeneration (AMD) in the European Union (EU), where AMD is the leading cause of legal blindness and visual impairment. Importantly, the second objective was to predict future EU prevalence and incidence figures out to the year 2050. ## How did tHey do it? The authors performed a systematic review and identified relevant articles in the literature: 22 prevalence but only four incidence studies. Since different studies used different AMD classification systems, the authors recategorised the data according to the Beckman Initiative for Macular Research system. 2 They then synthesised the data by meta-analysis to obtain prevalence and incidence estimates by AMD stage. Specifically, they used random-effects meta-analysis, which assumes that results vary between studies not just from random error but also from true variation (ie, 'heterogeneity', from differences in study protocols, regions, etc). Next, they performed random-effects meta-regression to investigate potential sources of heterogeneity. In this way, the authors derived population prevalence estimates, expressed

Who reads Study the past if you would define the future (Confucius)?

Author

Keenan, Tiarnan D. (author);Chew, Emily Y. (author)

Publisher

BMJ Publishing Group

Published

2020

Language

EN

ISBN

9782020315890

Field

Medicine (Health Sciences)