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Severity and mortality of COVID-19 infection in HIV-infected individuals: Preliminary findings from Iran by Sana Eybpoosh; Mahdi Afshari; Ali-Akbar Haghdoost; Parvin Afsar Kazerooni; Mohammad Mehdi Gouya; Katayoon Tayeri is a Medicine article available to read on EtoBox.
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**Background:** Higher mortality due to coronavirus disease 2019 (COVID-19) is reported among some immunocompromised patients; however, the relation between immunosuppression due to HIV infection and severity of COVID-19 infection remains unclear. We aimed to investigate the severity and mortality of COVID-19 infection in HIV-infected patients. **Methods:** This was a retrospective cohort study on all COVID-19 suspected and confirmed cases hospitlized in Iran between Febuary 19 (epidemic onset date) and April 8, 2020, whose data were recorded in the national database for Medical Care Monitoring Center. Hospitalized patients were followed from admittion to death/discharge. Patients’ HIV status was recorded based on their self report. Logistic and Cox regression models were used to evaluate the association between HIV infection and the severity (according to the Glascow-Coma Scale situation, need for intubation and hypoxemia) and mortality of COVID-19 infection, respectively. Analyses were performed separately for COVID-19 suspected and confirmed cases. **Results:** Out of 122 206 severe acute respiratory infection (SARI) cases, 90 were HIV-positive (0.07%), with a similar mean age (
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- Author
- Sana Eybpoosh; Mahdi Afshari; Ali-Akbar Haghdoost; Parvin Afsar Kazerooni; Mohammad Mehdi Gouya; Katayoon Tayeri
- Publisher
- Academic World Research
- Published
- 2021
- Language
- EN
- Field
- Medicine (Health Sciences)