Can I read 24: Beneficial Effect of Calcium Treatment for Hyperkalemia Is Mediated by Calcium-Dependent Conduction, Not “Membrane Stabilization” on EtoBox?

24: Beneficial Effect of Calcium Treatment for Hyperkalemia Is Mediated by Calcium-Dependent Conduction, Not “Membrane Stabilization” by J.S. Piktel; X. Wan; M. Infeld; D.S. Rosenbaum; L.D. Wilson is a Medicine article available to read on EtoBox.

What is 24: Beneficial Effect of Calcium Treatment for Hyperkalemia Is Mediated by Calcium-Dependent Conduction, Not “Membrane Stabilization” about?

Methods: We performed a retrospective review of a prospectively collected registry of consecutive patients with spontaneous ICH presenting to a single urban academic ED from February 2005 to October 2009. Patients were excluded from analysis if their goals of care were made comfort measures only (CMO) in the ED or they were not admitted to the ICU. The primary outcome was modified Rankin Scale (mRS) on hospital discharge. Secondary outcomes were hospital and ICU length of stay and hematoma expansion at 24 hours. We analyzed the relationship between EDLOS and discharge mRS using a non-parametric mixed model. Potential covariates were identified a priori for their clinical relevance, but excluded from the model if the p value of the Spearman correlation coefficient for their relationship either to EDLOS or to mRS were Ն 0.20. Covariates included in the final model were: Glasgow Coma Scale (GCS) on presentation, initial hematoma volume and need for endotracheal intubation. Results: During the study period, 616 subjects presented with spontaneous ICH. Of these, 34 were excluded for use of CMO orders, 4 were not admitted to an ICU, and 4 presented twice for recurrent ICH in this time fr

Who reads 24: Beneficial Effect of Calcium Treatment for Hyperkalemia Is Mediated by Calcium-Dependent Conduction, Not “Membrane Stabilization”?

Author

J.S. Piktel; X. Wan; M. Infeld; D.S. Rosenbaum; L.D. Wilson

Publisher

Elsevier Science; Elsevier ; Mosby Inc.; Elsevier BV (ISSN 1097-6760)

Published

2010

Language

EN

Field

Medicine (Health Sciences)