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About this document

Oncometabolites and Cancer Metabolism by Ibrahim Marmal is a document available to read on EtoBox.

The document discusses the role of oncometabolites in cancer, focusing on how mutations in Krebs cycle enzymes lead to abnormal metabolite accumulation and contribute to malignancy. It highlights mechanisms such as epigenetic alterations, pseudo-hypoxia, and the production of reactive oxygen species (ROS) that promote tumor progression. Additionally, it outlines diagnostic biomarkers for identifying mutations in IDH, FH, and SDH.

Author
Ibrahim Marmal
Language
EN