Can I read Adult onset of acute myeloid leukaemia (M6) in patients with Shwachman-Diamond syndrome on EtoBox?

Adult onset of acute myeloid leukaemia (M6) in patients with Shwachman-Diamond syndrome by Inderjeet Dokal; Simon Rule; Fred Chen; Mike Potter; John Goldman is a Medicine article available to read on EtoBox.

What is Adult onset of acute myeloid leukaemia (M6) in patients with Shwachman-Diamond syndrome about?

Three male patients (two of whom were brothers) with Shwachman‐Diamond (SDS) syndrome presented with acute myeloid leukaemia in adulthood. In all three cases there was trilineage myelodysplasia and the morphology was consistent with FAB subtype M6. SDS is an inherited bone marrow failure syndrome with a high propensity to leukaemic transformation. Since this may not occur until adulthood, SDS should be considered in the differential diagnosis of adults presenting with acute myeloid leukaemia, particularly where features of myelodysplasia are prominent.

Who reads Adult onset of acute myeloid leukaemia (M6) in patients with Shwachman-Diamond syndrome?

Author

Inderjeet Dokal; Simon Rule; Fred Chen; Mike Potter; John Goldman

Publisher

John Wiley and Sons; Wiley (Blackwell Publishing); Blackwell Publishing Inc.; Wiley (ISSN 0007-1048)

Published

1997

Language

EN

Field

Medicine (Health Sciences)