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What is Pentose Phosphate Pathway Overview about?

The Pentose Phosphate Pathway, also known as the pentose shunt, occurs in the cytosol and begins with glucose 6-phosphate, reconnecting with glycolysis to produce NADPH and ribose 5-phosphate for nucleotide biosynthesis. It has two phases, with the glucose 6-phosphate dehydrogenase reaction being the rate-limiting step, and is crucial for rapidly dividing cells and maintaining glutathione levels in erythrocytes. Deficiencies in this pathway can lead to conditions like hemolytic anemia, particularly in indiv

Author

Seema Hedaoo

Language

EN