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Histopathologic pitfalls of Mohs micrographic surgery and a review of tumor histology by Katlein França; Yasser Alqubaisy; Ashraf Hassanein; Keyvan Nouri; Torello Lotti is a Medicine article available to read on EtoBox.

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Mohs micrographic surgery is a specialized subset of staged surgical excisions with each subsequent stage being driven largely by the histologic findings of the previous stage. Therefore, it is imperative that histologic analysis is performed in an accurate manner. Frozen section and tissue flattening is a crucial step in Mohs surgery. Frozen sections introduce certain artifacts and these artifacts must be interpreted in the correct context. Basal and squamous cell carcinomas are the most common tumors encountered in Mohs micrographic surgery, and their histopathology is also associated with certain "pitfalls". Basal cell carcinoma should be distinguished from hair follicles, folliculocentric basaloid proliferations, poromas, nevus sebaceous, desmoplastic trichoepitheliomas, and spiradenomas, to name but a few histologic entities. Similarly, squamous cell carcinoma should be distinguished from hypertrophic actinic keratoses, pseudoepitheliomatous hyperplasia, sebaceous carcinoma, and microcystic adnexal carcinoma. In addition, there are numerous subtypes of basal cell and squamous carcinomas that the Mohs surgeon should be aware of due to differences in the biologic behavior of the

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Author

Katlein França; Yasser Alqubaisy; Ashraf Hassanein; Keyvan Nouri; Torello Lotti

Publisher

Springer Science and Business Media LLC

Published

2016

Language

EN

Field

Medicine (Health Sciences)