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Can I read 244. Interindividual Brain Morphology Deviations From Normative Trajectories in Psychopathy, Psychosis, and Violence on EtoBox?
244. Interindividual Brain Morphology Deviations From Normative Trajectories in Psychopathy, Psychosis, and Violence by Jaroslav Rokicki; Thomas Wolfers; Natalia Tesli; Christina Bell; Gabriela Hjell; Thomas Fisher-Vieler; Ingrid Melle; Ole Andreassen; Kirsten Rasmussen; Ingrid Agartz; Lars T. Westlye; Christine Friestad; Unn Haukvik is a Neuroscience article available to read on EtoBox.
What is 244. Interindividual Brain Morphology Deviations From Normative Trajectories in Psychopathy, Psychosis, and Violence about?
anxiety. However, direct human-animal translations of approach-avoidance conflict are surprisingly lacking, limiting the adoption of contemporary computational psychiatry approaches to understanding approach-avoidance conflict. To address this we sought to develop, and computationallymodel, a new translational assessment of approach-avoidance conflict in humans.Methods: Online participants (discovery n1⁄4369; replication n1⁄4629) performed a 2-armed-bandit reinforcement-learning (RL) task. The 'conflict' arm probabilistically produced both rewards (coins) and punishments (aversive sound); the 'safe' arm produced rewards only but at a lower rate. Participants rated task-induced anxiety alongside clinical symptom questionnaires. RL models were _x0000_t to participant's behaviour.Results: Consistent with approach-avoidance conflict, participants generally choose the more highly rewarded arm (discovery: b1⁄40.89,p<0.001; replication: b1⁄40.96,p<0.001) and avoided the conflict arm more as the probability of aversive outcomes increased (discovery: b1⁄4-0.36,p<0.001; replication: b1⁄4-0.52,p<0.001). The winning RL model included rewardspecific/threat-specific sensitivity and reward-specif
Who reads 244. Interindividual Brain Morphology Deviations From Normative Trajectories in Psychopathy, Psychosis, and Violence?
It is typically read by researchers, students, and practitioners in Neuroscience.
- Author
- Jaroslav Rokicki; Thomas Wolfers; Natalia Tesli; Christina Bell; Gabriela Hjell; Thomas Fisher-Vieler; Ingrid Melle; Ole Andreassen; Kirsten Rasmussen; Ingrid Agartz; Lars T. Westlye; Christine Friestad; Unn Haukvik
- Publisher
- Elsevier BV
- Published
- 2023
- Language
- EN
- Field
- Neuroscience (Life Sciences)