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The document discusses the role of guard columns in Supercritical Fluid Chromatography (SFC), highlighting their importance in extending column lifetime and improving system reliability, despite some drawbacks like cost and potential loss in efficiency. It also details various chiral stationary phases (CSPs) used in chiral SFC, including polysaccharide-based, cyclodextrin-based, macrocyclic glycopeptides, Pirkle-type, ion-exchange, and crown ether CSPs, each with unique mechanisms for enantiomeric separatio

Author

almasshafique7

Language

EN