Can I read G-Quadruplex DNA binding by a series of carbocyanine dyes on EtoBox?
G-Quadruplex DNA binding by a series of carbocyanine dyes by Sean M. Kerwin; Daekyu Sun; Jonathan T. Kern; Anupama Rangan; Pei Wang Thomas is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.
What is G-Quadruplex DNA binding by a series of carbocyanine dyes about?
We have examined a number of carbocyanine dyes for their ability to bind intramolecular G-quadruplex DNA structures (G4 0 -DNA) using a Taq polymerase stop assay. Of the five dyes examined, only one, N,N'-diethylthiacarbocyanine iodide (DTC), was found to bind to G4 0 -DNA. DTC was also the only dye found to inhibit human telomerase at 50 mM concentration.
Who reads G-Quadruplex DNA binding by a series of carbocyanine dyes?
It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.
- Author
- Sean M. Kerwin; Daekyu Sun; Jonathan T. Kern; Anupama Rangan; Pei Wang Thomas
- Publisher
- Elsevier Science; Elsevier ; Elsevier Ltd.; Elsevier BV (ISSN 0960-894X)
- Published
- 2001
- Language
- EN
- Field
- Biochemistry, Genetics and Molecular Biology (Life Sciences)