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This document reviews the molecular mechanisms of heavy metal tolerance in invertebrates, focusing on the role of transcriptional regulation and the metallothionein system. It highlights how regulatory changes, particularly in the promoter regions of genes, can lead to enhanced stress tolerance in response to heavy metal exposure. The study of the springtail Orchesella cincta serves as a model for understanding the evolution of metal tolerance through cis-regulatory changes in gene expression.

Author

Alanna Frick

Language

EN