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The study investigates the role of connective tissue growth factor (CTGF) in inducing apoptosis in the human breast cancer cell line MCF-7. It demonstrates that CTGF, regulated by transforming growth factor beta (TGF-b), significantly enhances apoptosis in MCF-7 cells, suggesting its potential as a mediator in TGF-b-induced cell death. The findings indicate that CTGF may play an important role in breast cancer biology by inhibiting cancer cell proliferation through apoptosis induction.
- Author
- widadabdulwaheed
- Language
- EN