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The Correlation Between Pretreatment Serum Hormone Levels and Treatment Outcome for Patients with Prostatic Cancer and Bony Metastasis by S.S. Chen; K.-K. Chen; A.T.L. Lin; Y.-H. Chang; H.H. Wu; L.S. Chang is a Medicine article available to read on EtoBox.

What is The Correlation Between Pretreatment Serum Hormone Levels and Treatment Outcome for Patients with Prostatic Cancer and Bony Metastasis about?

**Objective** To evaluate whether pretreatment serum hormone levels are a prognostic factor for prostatic cancer with bony metastasis under hormonal treatment. **Patients and methods** Between 1980 and 1994, 96 patients with prostate cancer and bony metastasis were included for an evaluation by a retrospective review of their charts. All 96 had received hormonal treatment after a diagnosis of metastatic prostatic carcinoma. Serum testosterone, luteinizing hormone (LH), follicle‐stimulating hormone (FSH) and prolactin were assessed before treatment. The patients were divided into two groups according to their response during the follow‐up. Group 1 (good response) had no change or resolution of metastatic lesion(s) on the bone scan and a declining prostate‐specific antigen (PSA) level. Group 2 had increased PSA or progression of metastatic lesion(s) on the bone scan. Tumours were graded as low (2–4), intermediate (5–7) and high (8–10) using the Gleason score. **Results** There were 43 patients in group 1 and 53 in group 2; the overall mean (sd) age was 72.5 (6.8) years and the follow‐up 29.5 (0.5) months. The respective mean (sd) levels of testosterone, LH, FSH and prolactin before t

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Author

S.S. Chen; K.-K. Chen; A.T.L. Lin; Y.-H. Chang; H.H. Wu; L.S. Chang

Publisher

John Wiley and Sons; Wiley (Blackwell Publishing); Blackwell Publishing Inc.; Wiley (ISSN 1464-4096)

Published

2002

Language

EN

Field

Medicine (Health Sciences)