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Bioaccessibility and Bioavailability Adjusted Dietary Exposure of Cadmium for Local Residents from a High-level Environmental Cadmium Region by Fei-Fei Xu; Jia Song; Yue-Qi Li; Yue-Fei Lai; Jun Lin; Jia-Liang Pan; Hui-Qin Chi; Yan Wang; Zi-Yin Li; Gao-Qiang Zhang; Zhan-Fan Cai; Xu-Xia Liang; An-De Ma; Chu-Ting Tan; Wei-Liang Wu; Xing-Fen Yang is a Environmental Science article available to read on EtoBox.

What is Bioaccessibility and Bioavailability Adjusted Dietary Exposure of Cadmium for Local Residents from a High-level Environmental Cadmium Region about?

The critical health risks caused by cadmium (Cd) via dietary exposure are commonly assessed by detecting Cd concentrations in foods. Differently, in this study, the bioaccessibility and bioavailability of Cd in major local harvests were introduced to assess the dietary exposure of local residents from a high-level environmental Cd region. The results indicated that certain Cd was released into the digestive juice after in vitro digestion with a bioaccessibility of 20-63% for rice and 3-32% for leafy vegetables, and the released portion was partially absorbed by Caco-2 cells with a bioavailability of 2-21% for rice and 0.2-13% for leafy vegetables. The results obtained from the toxicokinetic model revealed that the predicted urinary Cd values from the estimated daily intake (EDI) of Cd, which accounted for bioaccessibility and bioavailability, were consistent with the actual measured values, and the EDIs were considerably lower than the acceptable daily intake. This suggests that the bioaccessibility and bioavailability adjusted dietary Cd exposure should be more precise. The key issues addressed in our study implores that a potential health risk cannot be neglected in people with h

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Author

Fei-Fei Xu; Jia Song; Yue-Qi Li; Yue-Fei Lai; Jun Lin; Jia-Liang Pan; Hui-Qin Chi; Yan Wang; Zi-Yin Li; Gao-Qiang Zhang; Zhan-Fan Cai; Xu-Xia Liang; An-De Ma; Chu-Ting Tan; Wei-Liang Wu; Xing-Fen Yang

Publisher

Elsevier BV

Published

2021

Language

EN

Field

Environmental Science (Physical Sciences)