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Incidence of sex chromosome abnormalities in spermatozoa from patients entering an IVF or ICSI protocol by Ritsa T. Storeng; Michelle Plachot; Didier Theophile; Jacqueline Mandelbaum; Joëlle Belaisch‐ALLART; Michel Vekemans is a Medicine article available to read on EtoBox.

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## Objective: The objective of this study was the determination of sex chromosome aneuploidy frequency in spermatozoa from patients included in an in vitro fertilization (ivf) or intra cytoplasmic sperm injection (icsi) protocol. ## Methods: Spermatozoa from nineteen patients, including patients with normal seminal parameters according to world health organization (who) criteria and patients exhibiting abnormal seminal parameters, were analyzed by dual color fluorescence in situ hybridization (fish) for aneuploidies of the x and y chromosomes. our technique, using only probes for sex chromosomes and not for autosomes, does not discriminate between hyperhaploid and diploid sperm nuclei. the results were analyzed in two different ways: in relation to the semen status, denoted normal or abnormal and with regard to the ability of the sperm to fertilize oocytes when ivf or icsi was performed. ## Results: Abnormal semen showed a significant increase in the overall rate of sperm nuclei with xy, xx and yy sex chromosome complements, 1.59% compared to normal semen, 0.78% (p<0.02). semen shown to be able to fertilize oocytes only by icsi showed a higher incidence of xy-bearing spermatozoa, 1

Who reads Incidence of sex chromosome abnormalities in spermatozoa from patients entering an IVF or ICSI protocol?

Author

Ritsa T. Storeng; Michelle Plachot; Didier Theophile; Jacqueline Mandelbaum; Joëlle Belaisch‐ALLART; Michel Vekemans

Publisher

Informa plc; Wiley (Blackwell Publishing); Wiley-Blackwell; Wiley (ISSN 0001-6349)

Published

1998

Language

EN

Field

Medicine (Health Sciences)