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What is Linezolid Pharmacokinetics in VAP Patients about?

This study investigates the pharmacokinetics and alveolar diffusion of linezolid administered via continuous infusion in critically ill patients with ventilator-associated pneumonia (VAP). The results indicate that a daily infusion of 1200 mg of linezolid achieves satisfactory serum and epithelial lining fluid concentrations, exceeding the susceptibility breakpoint for Staphylococcus aureus. However, the clinical benefits of continuous infusion compared to standard intermittent dosing remain to be establish

Author

Boselli

Language

EN