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Can I read Sex differences in initial treatment for genital extramammary Paget disease in the United States: A systematic review on EtoBox?
Sex differences in initial treatment for genital extramammary Paget disease in the United States: A systematic review by Supriya Rastogi; Rebecca Thiede; Lauren M. Sadowsky; Tammy Hua; Akash Rastogi; Corinne Miller; Bethanee J. Schlosser is a Medicine article available to read on EtoBox.
What is Sex differences in initial treatment for genital extramammary Paget disease in the United States: A systematic review about?
Background: Surgery is the standard treatment for genital extramammary Paget disease (gEMPD). Objective: To determine if gEMPD treatments and outcomes differ by sex and US region. Methods: A systematic review was performed of all English-language studies on initial gEMPD treatment in Medline via PubMed, Embase, Cochrane Library, Web of Science, and ClinicalTrials.gov. At least 2 reviewers performed title and abstract review and data extraction. Surgical categories included total skinning procedures, partial skinning procedures, Mohs micrographic surgery (MMS), or unspecified surgery. Chi-squared tests of association were used for comparisons. Results: A total of 60 studies comprising 302 (79.7%) female and 77 (20.3%) male patients met criteria. Women were most often initially recommended partial skinning procedures. In all, 74 (24.5%) women and 0 men underwent a total skinning procedure. Men were more likely to be offered MMS than women (40.3% vs 1.9%, P \.0001), despite men having a significantly greater extent of disease involving the perineum and perianal skin (21.1% vs 1.7%, P \ .0001). Treatment recommendations varied by US region. Limitations: Only 20 states were represented.
Who reads Sex differences in initial treatment for genital extramammary Paget disease in the United States: A systematic review?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Supriya Rastogi; Rebecca Thiede; Lauren M. Sadowsky; Tammy Hua; Akash Rastogi; Corinne Miller; Bethanee J. Schlosser
- Publisher
- Elsevier BV
- Published
- 2019
- Language
- EN
- Field
- Medicine (Health Sciences)