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What is RNA Targets of Argonaute2 in Development about?

This dissertation by David Jee explores the role of mammalian Argonaute2 in RNA slicing during development, highlighting the discovery of a novel locus (mir-486) that requires Ago2-mediated slicing for its maturation. The research includes genome-wide profiling of small RNA targets and the generation of mouse models to understand the in vivo requirements for slicing, revealing its significance in the maturation and homeostasis of red blood cells. Overall, the work provides insights into the evolutionary rat

Author

Bahlibi

Language

EN