Can I read Focus On... on EtoBox?

Focus On... is a Medicine article available to read on EtoBox.

What is Focus On... about?

Studies evaluating the role of routine second-look endoscopy in patients with acute upper gastrointestinal bleeding (UGIB) due to peptic ulcer disease (PUD) have reported conflicting results. This meta-analysis evaluates the usefulness of routine second-look endoscopy in these patients. The authors reviewed several databases from inception to September 15, 2020 to identify randomized controlled trials (RCTs) that compared routine second-look endoscopy with no planned second-look endoscopy in patients with acute UGIB due to PUD. The outcomes of interest were recurrent bleeding, mortality, need for surgery, and mean number of units of blood transfused. For categorical variables, the authors calculated pooled risk ratios (RR) with 95% confidence intervals (CI); for continuous variables, they calculated standardized mean difference (SMD) with 95% CI. Data were analyzed using a random effects model. GRADE framework was used to ascertain the quality of evidence. Nine RTCs were included comprising 1452 patients; 726 patients underwent planned/routine second-look endoscopy and 726 did not. The authors found no significant difference in recurrent bleeding (RR, 0.79; 95% CI, 0.51-1.23), need

Who reads Focus On...?

Publisher

Elsevier BV

Published

2021

Language

EN

Field

Medicine (Health Sciences)