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Perceived benefits and barriers to implementing precision preventive care: Results of a national physician survey by Jason L. Vassy; Benjamin J. Kerman; Elizabeth J. Harris; Amy A. Lemke; Marla L. Clayman; Ashley A. Antwi; Katharine MacIsaac; Thomas Yi; Charles A. Brunette is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.
What is Perceived benefits and barriers to implementing precision preventive care: Results of a national physician survey about?
Polygenic risk scores (PRS) may improve risk-stratification in preventive care. Their clinical implementation will depend on primary care physicians' (PCPs) uptake. We surveyed PCPs in a national physician database about the perceived clinical utility, benefits, and barriers to the use of PRS in preventive care. Among 367 respondents (participation rate 96.3%), mean (SD) age was 54.9 (12.9) years, 137 (37.3%) were female, and mean (SD) time since medical school graduation was 27.2 (13.3) years. Respondents reported greater perceived utility for more clinical action (e.g., earlier or more intensive screening, preventive medications, or lifestyle modification) for patients with high-risk PRS than for delayed or discontinued prevention actions for low-risk patients (p < 0.001). Respondents most often chose out-of-pocket costs (48%), lack of clinical guidelines (24%), and insurance discrimination concerns (22%) as extreme barriers. Latent class analysis identified 3 subclasses of respondents. Skeptics (n = 83, 22.6%) endorsed less agreement with individual clinical utilities, saw patient anxiety and insurance discrimination as significant barriers, and agreed less often that PRS could
Who reads Perceived benefits and barriers to implementing precision preventive care: Results of a national physician survey?
It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.
- Author
- Jason L. Vassy; Benjamin J. Kerman; Elizabeth J. Harris; Amy A. Lemke; Marla L. Clayman; Ashley A. Antwi; Katharine MacIsaac; Thomas Yi; Charles A. Brunette
- Publisher
- Springer Science and Business Media LLC
- Published
- 2023
- Language
- EN
- Field
- Biochemistry, Genetics and Molecular Biology (Life Sciences)