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Prucalopride vs Lactulose for Clozapine Constipation by Asyraf Zai is a document available to read on EtoBox.
What is Prucalopride vs Lactulose for Clozapine Constipation about?
This study compares the efficacy and safety of Prucalopride and Lactulose in treating Clozapine-induced constipation in patients with treatment-resistant schizophrenia. Results showed that Prucalopride significantly improved bowel movements compared to Lactulose, with 85.7% of patients achieving ≥3 spontaneous complete bowel movements by Week 4. The study highlights the need for effective management of constipation, a common side effect of Clozapine, to reduce associated morbidity and mortality.
- Author
- Asyraf Zai
- Language
- EN