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Combined Use of Multimodal Techniques for the Resection of Glioblastoma Involving Corpus Callosum by Meng Cui; Hewen Chen; Guochen Sun; Jialin Liu; Meng Zhang; Hepu Lin; Caihong Sun; Xiaodong Ma is a Medicine article available to read on EtoBox.

What is Combined Use of Multimodal Techniques for the Resection of Glioblastoma Involving Corpus Callosum about?

## Abstract ## Purpose To compare the multimodal techniques (including neuronavigation, intraoperative MRI [iMRI], and neuromonitoring [IONM]) and conventional approach (only guided by neuronavigation) in removing glioblastoma (GBM) with corpus callosum (CC) involvement (ccGBM), their effectiveness and safety were analyzed and compared. ## Methods Electronic medical records were retrospectively reviewed for ccGBM cases treated in our hospital between January 2016 and July 2020. Patient demographics, tumor characteristics, clinical outcomes, extent of resection (EOR), progression-free survival (PFS), and overall survival (OS) were obtained and compared between the multimodal group (used multimodal techniques) and the conventional group (only used neuronavigation). Both groups only included patients that had maximal safe resection (not biopsy). Postoperative radiochemotherapy was also performed or not. Univariate and multivariate analyses were performed to identify significant prognostic factors and optimal EOR threshold. ## Results Finally 56 cases of the multimodal group and 21 cases of the conventional group were included. The multimodal group achieved a higher median EOR (100% ve

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Author

Meng Cui; Hewen Chen; Guochen Sun; Jialin Liu; Meng Zhang; Hepu Lin; Caihong Sun; Xiaodong Ma

Publisher

Springer Science and Business Media LLC

Published

2021

Language

EN

Field

Medicine (Health Sciences)