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Can I read Extreme warfarin sensitivity in siblings associated with multiple cytochrome P450 polymorphisms on EtoBox?
Extreme warfarin sensitivity in siblings associated with multiple cytochrome P450 polymorphisms by Arash Rafii Tabrizi; Sean D. McGrath; Morey A. Blinder; Timothy G. Buchman; Barbara A. Zehnbauer; Bradley D. Freeman is a Medicine article available to read on EtoBox.
What is Extreme warfarin sensitivity in siblings associated with multiple cytochrome P450 polymorphisms about?
## Abstract Warfarin use is complicated by an erratic dose response. Warfarin is metabolized by two distinct subfamilies of the cytochrome P450 (CYP) complex. We describe two siblings with extreme sensitivity to warfarin who share an unusual CYP genotype. These individuals illustrate both the importance of genetics in influencing the metabolism of warfarin as well as the potential utility of genetic testing as a guide to prescribing this medication. Am. J. Hematol. 67:144–146, 2001. © 2001 Wiley‐Liss, Inc.
Who reads Extreme warfarin sensitivity in siblings associated with multiple cytochrome P450 polymorphisms?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Arash Rafii Tabrizi; Sean D. McGrath; Morey A. Blinder; Timothy G. Buchman; Barbara A. Zehnbauer; Bradley D. Freeman
- Publisher
- John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley; Research Square (ISSN 0361-8609)
- Published
- 2001
- Language
- EN
- Field
- Medicine (Health Sciences)