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Susceptibility to adjuvant arthritis in da and F~344~ RATS. A dominant trait controlled by an autosomal gene locus linked to the major histocompatibility complex by Jack R. Battisto; R. N. Smith; Karla Beckman; Mona Sternlicht; Wanda L. Welles is a Medicine article available to read on EtoBox.

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## Abstract The heritability of adjuvant‐induced arthritis in rats of the DA and Fisher 344 strains was examined. Development of arthritic lesions in response to a single injection of supplemented Freund's complete adjuvant has been found to be controlled by an autosomal, dominant gene locus, Ar. The capacity to respond was present in DA rats and absent in our Fisher rats. Ar has been found to be linked to the major histocompatibility complex genes with which it exhibits a high rate of recombination.

Who reads Susceptibility to adjuvant arthritis in da and F~344~ RATS. A dominant trait controlled by an autosomal gene locus linked to the major histocompatibility complex?

Author

Jack R. Battisto; R. N. Smith; Karla Beckman; Mona Sternlicht; Wanda L. Welles

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0004-3591)

Published

1982

Language

EN

Field

Medicine (Health Sciences)