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COX‐1 and ‐2 activity of rose hip by A. K. Jäger; I.M.S. Eldeen; J. van Staden is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.
What is COX‐1 and ‐2 activity of rose hip about?
## Abstract The objective of this study was to investigate whether the clinically observed efficacy of rose hip in the treatment of osteoarthritis is due to inhibition of cyclooxygenase‐1 and ‐2. Water, methanol, dichloromethane and hexane extracts of rose hip were tested for __in vitro__ COX‐1 and 2 activity. The organic solvent extracts showed good inhibition of both COX‐1 and 2. The methanol extract was most active in both assays with IC~50~ values of 12 μg/mL for COX‐1 and 19 μg/mL for COX‐2. The clinically observed effect might be due to inhibition of cyclooxygenase. Copyright © 2007 John Wiley & Sons, Ltd.
Who reads COX‐1 and ‐2 activity of rose hip?
It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.
- Author
- A. K. Jäger; I.M.S. Eldeen; J. van Staden
- Publisher
- John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0951-418X)
- Published
- 2007
- Language
- EN
- Field
- Biochemistry, Genetics and Molecular Biology (Life Sciences)