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ChemInform Abstract: Unexpected Aldol Condensations under Williamson Arylmethyl Ether Synthesis Conditions. by A. L. SILVA; B. QUIROZ; L. A. MALDONADO is a Chemistry article available to read on EtoBox.

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Unexpected Aldol Condensations under Williamson Arylmethyl Ether Synthesis Conditions. -O-Methylation of 5-bromosalicylaldehyde (Ia) under standard conditions using dimethyl sulfate in refluxing acetone for 2h gives the expected methyl ether (Va) in high yield. However, prolonged reflux leads to the unexpected formation of aldol product (IVa). The analogous phenolic aldehydes (Ib) and (Ic) undergo the same reaction to give the aldols (IVb) and (IVc). -(SILVA, A.

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Author
A. L. SILVA; B. QUIROZ; L. A. MALDONADO
Publisher
John Wiley and Sons; Wiley (John Wiley & Sons); Wiley (ISSN 0931-7597)
Published
1998
Language
EN
Field
Chemistry (Physical Sciences)

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